Fresh vs Frozen

Fresh vs frozen cell products

Both fresh and cryopreserved cells are used in regenerative medicine. What matters is documentation and handling, not marketing labels.

Cryopreserved cell product vial
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Two formats

Fresh

Cells administered shortly after processing. Requires tight scheduling, careful logistics and release testing within the use window.

Frozen (cryopreserved)

Cells stored in vapor-phase liquid nitrogen and thawed before use. Requires validated cryoprotectant, thaw protocol and post-thaw viability data.

Was viability measured before administration?

What is the post-thaw viability for frozen products?

What is the storage temperature and duration?

Is the cold chain documented?

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